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April 11, 2011AnesthesiologyOpen Access

Perioperative Stroke and Associated Mortality after Noncardiac, Nonneurologic Surgery

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Why the study?

What are the incidence, predictors, and mortality impact of perioperative stroke in patients undergoing noncardiac, nonneurologic surgery?

Population

523,059 patients undergoing noncardiac, nonneurologic surgery from the American College of Surgeons National…

Design

Cohort

Follow-up

30 days

Authors

GMGeorge A. MashourASAmy ShanksSKSachin Kheterpal

Discussion

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Overview

High mortality link warrants preoperative risk stratification; leaves open targeted prevention trials in noncardiac nonneurologic surgery.

Structured PICO

What are the incidence, predictors, and mortality impact of perioperative stroke in patients undergoing noncardiac, nonneurologic surgery?

P
Population
523,059 patients undergoing noncardiac, nonneurologic surgery from the American College of Surgeons National Surgical Quality Improvement Program database in the United States (derivation cohort n=350,031; validation cohort n=173,028).
O
Outcome
Incidence of perioperative stroke and 30-day mortalityhard clinical

Perioperative stroke after noncardiac, nonneurologic surgery is rare (0.1%) but is associated with a severe 8-fold increase in 30-day mortality, emphasizing the importance of preoperative risk stratification.

Cite This Study

Mashour et al. (2011) studied this question.

synapsesocial.com/papers/6a702bb2ce524a4339c3eff9https://doi.org/10.1097/aln.0b013e318216e7f4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ischemic stroke after surgical procedures1998 · 173 citations
  2. 2Mechanisms of perioperative cerebral infarction.1982 · 115 citations
  3. 3Postoperative cerebrovascular accidents in general surgery1988 · 101 citations
  4. 4Preexisting Morbidity as an Independent Risk Factor for Perioperative Acute Thromboembolism Syndrome2005 · 47 citations
  5. 5Perioperative Strokes and β-Blockade2009 · 27 citations