Clinical, biomarker, and genetic predictors of specific types of atrial fibrillation in a community-based cohort: data of the PREVEND study
Why the study?
What are the clinical, biomarker, and genetic predictors of specific types of incident atrial fibrillation in a community-based cohort?
Population
8042 individuals from the community-based PREVEND study cohort, mean age 48.5 ± 12.4 years, 50% men. 319 had…
Design
Cohort
Authors
Discussion
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Member takes
Implication
Distinct predictors for AF subtypes support subtype-specific stratification; leaves open whether targeting modifiable factors alters progression.
Structured PICO
What are the clinical, biomarker, and genetic predictors of specific types of incident atrial fibrillation in a community-based cohort?
P
Population
8042 individuals from the community-based PREVEND study cohort, mean age 48.5 ± 12.4 years, 50% men. 319 had incident AF.
O
Outcome
Development of specific types of incident atrial fibrillation (AF without 2-year recurrence, self-terminating AF, and non-self-terminating AF)hard clinical
Different types of incident atrial fibrillation have distinct clinical, biomarker, and genetic predictors, suggesting different underlying pathophysiological mechanisms.
Cite This Study
Hobbelt et al. (2016) studied this question.