July 13, 2006European Heart Journal
Global characterization of coronary plaque rupture phenotype using three-vessel intravascular ultrasound radiofrequency data analysis
Why the study?
What are the global characteristics and plaque phenotypes of patients with versus without coronary plaque rupture assessed by three-vessel IVUS-VH?
Population
40 patients undergoing three-vessel intravascular ultrasound radiofrequency data analysis (IVUS-VH)
Comparison
Three-vessel intravascular ultrasound… vs Patients without evidence of plaque rupture
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Higher BMI and plaque burden associated with rupture on three-vessel IVUS-VH; hypothesis-generating for vulnerability markers, needs prospective validation.
Structured PICO
What are the global characteristics and plaque phenotypes of patients with versus without coronary plaque rupture assessed by three-vessel IVUS-VH?
P
Population
40 patients undergoing three-vessel intravascular ultrasound radiofrequency data analysis (IVUS-VH)
I
Intervention
Three-vessel intravascular ultrasound radiofrequency data analysis (IVUS-VH)
C
Comparator
Patients without evidence of plaque rupture
O
Outcome
Global characteristics (BMI, plaque burden, lumen cross-sectional area) and plaque phenotype (necrotic core content)surrogate
Patients with coronary plaque rupture exhibit higher BMI, greater plaque burden, and higher necrotic core content as assessed by three-vessel IVUS-VH.
Cite This Study
Rodríguez-Granillo et al. (2006) studied this question.