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March 15, 2005Anesthesia & Analgesia

Interscalene Brachial Plexus Block with Bupivacaine and Ropivacaine in Patients with Chronic Renal Failure: Diaphragmatic Excursion and Pulmonary Function Changes

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Why the study?

Does ropivacaine compared to bupivacaine improve pulmonary function changes in patients with chronic renal failure undergoing interscalene brachial plexus block?

Population

42 patients with chronic renal failure undergoing interscalene brachial plexus anesthesia for creation of…

Comparison

30 mL of 0.33% ropivacaine for interscalene… vs 30 mL of 0.33% bupivacaine for interscalene…

Design

RCT, randomly allocated, double-blind

Authors

FAFatiş AltıntaşHaseki Eğitim ve Araştırma HastanesiFGFunda GümüşDicle UniversityGKGüner KayaIstanbul University-Cerrahpaşa

Discussion

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Implication

Favors ropivacaine over bupivacaine to limit pulmonary impairment in chronic renal failure interscalene blocks; extends agent comparisons to this population.

Structured PICO

Does ropivacaine compared to bupivacaine improve pulmonary function changes in patients with chronic renal failure undergoing interscalene brachial plexus block?

P
Population
42 patients with chronic renal failure undergoing interscalene brachial plexus (IBP) anesthesia for creation of arteriovenous fistulas
I
Intervention
30 mL of 0.33% ropivacaine for interscalene brachial plexus block
C
Comparator
30 mL of 0.33% bupivacaine for interscalene brachial plexus block
O
Outcome
Anesthetic characteristics and pulmonary function changes (forced vital capacity, forced expiratory volume at 1 second, and peak expiratory flow)surrogate

In patients with chronic renal failure undergoing interscalene brachial plexus block, 0.33% ropivacaine results in less impairment of pulmonary function compared to 0.33% bupivacaine.

Cite This Study

Altıntaş et al. (2005) studied this question.

synapsesocial.com/papers/6a702ddd5d37378ac1dd3f77https://doi.org/10.1213/01.ane.0000154443.68396.70
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Efficacy of Axillary Block for Surgical Procedures About the Elbow1996 · 74 citations
  2. 2One Hundred Percent Incidence of Hemidiaphragmatic Paresis Associated With Interscalene Brachial Plexus Anesthesia as Diagnosed by Ultrasonography1991 · 619 citations
  3. 3Normal Diaphragmatic Motion and the Effects of Body Composition2004 · 110 citations
  4. 4Inspiratory muscle function in unilateral diaphragmatic paralysis.1986 · 96 citations
  5. 5A Comparison of Ropivacaine 0.5% and Bupivacaine 0.5% for Brachial Plexus Block1991 · 156 citations