March 15, 1995Biochemical JournalOpen Access

The cross-regulation of Gi-protein by cholera toxin involves a phosphorylation by protein kinase A

View Full Paper

Ask AI

Bookmark

Population

Alveolar macrophages

Design

Preclinical

Authors

RLRomuald LevistreCentre National de la Recherche Scientifique MBMarie BerguerandCentre National de la Recherche Scientifique GBG. BéréziatCentre National de la Recherche Scientifique

Discussion

Member takes

Implication

Suggests PKA phosphorylation of Gi as cholera toxin mechanism; leaves open translation to human cardiovascular arachidonic acid signaling.

Structured PICO

Population

Alveolar macrophages

Intervention

Cholera toxin pretreatment

Outcome

Phosphorylation of Gi alpha by protein kinase A (PKA) and functional activity of Gisurrogate

The study reveals that cholera toxin exerts its inhibitory effect on arachidonic acid release through the phosphorylation of Gi alpha by protein kinase A.

Cite This Study

Levistre et al. (1995) studied this question.

synapsesocial.com/papers/6a702e2aac440176ef28d38e https://doi.org/10.1042/bj3060765

View Full Paper

Ask AI

Bookmark

Implication

Suggests PKA phosphorylation of Gi as cholera toxin mechanism; leaves open translation to human cardiovascular arachidonic acid signaling.

The cross-regulation of Gi-protein by cholera toxin involves a phosphorylation by protein kinase A

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The cross-regulation of Gi-protein by cholera toxin involves a phosphorylation by protein kinase A

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider