What question did this study set out to answer?

September 1, 2015Interventional Medicine and Applied ScienceOpen Access

Echocardiographic assessment of right ventricular functions in nondiabetic normotensive hemodialysis patients

View Full Paper

Ask AI

Bookmark

Why the study?

Does end-stage renal disease undergoing hemodialysis affect right ventricular echocardiographic parameters in nondiabetic, normotensive patients compared to healthy controls?

Population

45 nondiabetic, normotensive patients with end-stage renal disease undergoing hemodialysis and 39 healthy…

Comparison

End-stage renal disease undergoing hemodialysis vs Healthy age and sex-matched control subjects

Design

Cross-sectional

Authors

YKYusuf KaravelioğluInterventional / Structural Cardiology SÖSultan ÖzkurtEskişehir Osmangazi University MKMacit KalçıkInterventional / Structural Cardiology

Discussion

Member takes

Implication

RV parameters merit attention in normotensive nondiabetic HD patients; leaves open whether routine assessment alters outcomes.

Key Points

To evaluate right ventricular structural and functional echocardiographic parameters in nondiabetic, normotensive patients with end-stage renal disease undergoing maintenance hemodialysis.
Enrolled 45 nondiabetic, normotensive end-stage renal disease patients receiving hemodialysis (24 women; mean age 52.4 ± 12.4 years) and 39 age- and sex-matched healthy controls (22 women; mean age 50.3 ± 6.6 years).
Performed comprehensive echocardiography—including M-mode, two-dimensional, pulsed, continuous wave, and tissue Doppler imaging—on the non-dialysis days between treatments.
Right ventricular systolic indices were significantly lower in patients than controls, including fractional area change (p < 0.001) and tricuspid annular plane systolic excursion (p = 0.003).
Diastolic and combined performance markers deteriorated in hemodialysis patients, with lower tricuspid E velocity (p = 0.007), E/A ratio (p = 0.005), and annular E´ velocity (p < 0.001), alongside higher RV myocardial performance index (p = 0.007) and E/E´ ratio (p = 0.005).
Right ventricular diastolic area (p < 0.001), mean pulmonary artery pressure (p < 0.001), and systolic pulmonary artery pressure (p = 0.006) were significantly increased in patients compared to controls.

Structured PICO

Does end-stage renal disease undergoing hemodialysis affect right ventricular echocardiographic parameters in nondiabetic, normotensive patients compared to healthy controls?

Population

45 nondiabetic, normotensive patients with end-stage renal disease (ESRD) undergoing hemodialysis (24 women; mean age 52.4 ± 12.4 years) and 39 healthy age and sex-matched control subjects (22 women; mean age 50.3 ± 6.6 years).

Intervention

End-stage renal disease undergoing hemodialysis

Comparator

Healthy age and sex-matched control subjects

Outcome

Echocardiographic parameters of right ventricular (RV) systolic and diastolic functionsurrogate

Nondiabetic, normotensive patients with ESRD on hemodialysis exhibit deteriorated right ventricular systolic and diastolic function compared to healthy controls.

Cite This Study

Karavelioğlu et al. (2015) studied this question.

synapsesocial.com/papers/6a702f9fe5469ee92be0efe7 https://doi.org/10.1556/1646.7.2015.3.2

View Full Paper

Ask AI

Bookmark

Echocardiographic assessment of right ventricular functions in nondiabetic normotensive hemodialysis patients

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Echocardiographic assessment of right ventricular functions in nondiabetic normotensive hemodialysis patients

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider