Why the study?
What are the comparative hemodynamic effects of different vasopressor and vasodilator drugs used in circulatory shock?
Comparison
Vasopressor and vasodilator drugs including… vs Comparison among different classes of vasoactive…
Design
Review
Authors
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Supports spectrum-based vasoactive drug selection in shock; leaves open optimal choices pending randomized trials.
What are the comparative hemodynamic effects of different vasopressor and vasodilator drugs used in circulatory shock?
Viewing the effects of vasoactive drugs as a hemodynamic spectrum, rather than just by their pressor response, resolves the apparent paradox between vasopressor and vasodilator therapy in circulatory shock.
Calton M. Lewis (1969) studied this question.
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