Why the study?
Do cTnI and third-generation cTnT assays remain cardiospecific in the presence of exercise-induced skeletal muscle damage?
Population
8 highly trained male triathletes, mean age 29 +/- 9 years
Comparison
Two bouts of exercise: a maximal-ramping… vs Baseline (rest)
Design
Cohort
Follow-up
48 hours postexercise
Authors
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cTn assays retain cardiospecificity after exercise-induced muscle damage; supports reliability but leaves open broader validation in athletes and patients.
Do cTnI and third-generation cTnT assays remain cardiospecific in the presence of exercise-induced skeletal muscle damage?
The third-generation cTnT and cTnI assays remain highly cardiospecific and can reliably detect cardiac damage even in the presence of elevated total CK and CKMB associated with exercise-induced skeletal muscle damage.
Shave et al. (2002) studied this question.
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