What question did this study set out to answer?

To model and evaluate the precise influence of age and seasonality on the acquisition, carriage rates, and carriage duration of Streptococcus pneumoniae during the first 24 months of life.

October 1, 1982American Journal of Epidemiology

Epidemiologic Studies of Streptococcus Pneumoniae in Infants

View Full Paper

Ask AI

Bookmark

Authors

BGBarry M. GrayIllinois College MTMalcolm E. TurnerGrady Memorial Hospital HDHugh C. DillonNorfolk and Norwich University Hospital

Discussion

Member takes

Implication

Cohort study reveals winter peaks in Streptococcus pneumoniae acquisition and age-dependent carriage rates in infants, highlighting seasonal drivers of early bacterial transmission.

Key Points

To model and evaluate the precise influence of age and seasonality on the acquisition, carriage rates, and carriage duration of Streptococcus pneumoniae during the first 24 months of life.
Followed a birth cohort of infants enrolled between November 1974 and December 1975 in Birmingham, Alabama, throughout their first 24 months of life.
Constructed multiple regression models utilizing original observational data to quantify the effects of age and calendar season on pneumococcal acquisition rates, duration of carriage, and overall carriage rates.
Pneumococcal acquisition exhibited pronounced seasonality characterized by a marked winter peak and summer nadir.
Acquisition rates increased with advancing infant age while carriage duration decreased, driving a sharp increase in total carriage rate up to nine months of age before plateauing.
Multiple regression models demonstrated strong fit to the empirical data, although age and season accounted for only a relatively small fraction of the overall variance.

Cite This Study

Gray et al. (1982) studied this question.

synapsesocial.com/papers/6a70363ce71d69abee0873bf https://doi.org/10.1093/oxfordjournals.aje.a113452

View Full Paper

Ask AI

Bookmark

Implication

Cohort study reveals winter peaks in Streptococcus pneumoniae acquisition and age-dependent carriage rates in infants, highlighting seasonal drivers of early bacterial transmission.

Epidemiologic Studies of Streptococcus Pneumoniae in Infants

Discussion

Member takes

Implication

Key Points

Cite This Study

Epidemiologic Studies of Streptococcus Pneumoniae in Infants

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider