Why the study?
Does adding serum cystatin C or creatinine to Framingham risk score variables improve prediction of incident cardiovascular disease in adults without clinical CVD?
Population
6,653 adults without clinical cardiovascular disease from the Multi-Ethnic Study of Atherosclerosis. Mean…
Comparison
Addition of serum cystatin C or creatinine to… vs Framingham risk score variables (FRSVs) alone
Design
Cohort
Follow-up
6 years
Authors
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Adding cystatin C or creatinine to FRSVs does not enhance CVD prediction; leaves open whether kidney markers aid risk stratification in primary prevention.
Does adding serum cystatin C or creatinine to Framingham risk score variables improve prediction of incident cardiovascular disease in adults without clinical CVD?
Adding cystatin C or serum creatinine to standard Framingham risk score variables does not improve cardiovascular risk prediction in asymptomatic adults.
Ito et al. (2011) studied this question.
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