May 12, 1998Circulation
Prediction of Coronary Heart Disease Using Risk Factor Categories
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Implication
Prospective study examines risk factor categories for predicting coronary heart disease in a community cohort, suggesting effective guidelines.
Key Points
- The research aims to explore the relationship between blood pressure and cholesterol categories with coronary heart disease risk and to develop predictive algorithms.
- Prospective, single-center design with a community-based cohort of 5345 individuals aged 30 to 74 years
- 12 years of follow-up with assessments of blood pressure and cholesterol levels (JNC-V and NCEP categories)
- Sex-specific prediction equations formulated for CHD risk based on multiple risk factors including age, diabetes, and smoking.
- 383 men and 227 women developed CHD over 12 years, significantly linked to blood pressure and cholesterol categories (P<.001)
- Approximately 28% of CHD events in men and 29% in women were linked to blood pressure exceeding ≥130/85 mmHg
- Adjusted attributable risk associated with elevated total cholesterol (≥200 mg/dL) was 27% in men and 34% in women.
Cite This Study
Wilson et al. (1998) studied this question.