What question did this study set out to answer?

The study aims to assess the effectiveness of a risk function for predicting coronary heart disease in middle-aged and older adults.

August 8, 1977JAMA

Predicting Coronary Heart Disease in Middle-Aged and Older Persons

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Why the study?

Can a risk function based on lipids, blood pressure, LVH, and diabetes predict subsequent coronary heart disease in middle-aged and older persons?

Population

2,470 adults, aged 49 to 82 years, free of coronary heart disease at baseline.

Design

Cohort

Authors

TGTavia GordonGeneral / Preventive / Lipids

Discussion

Member takes

Implication

Risk stratification by deciles concentrates most CHD events in highest-risk groups; supports prediction models but leaves open effects on clinical outcomes.

Key Points

The study aims to assess the effectiveness of a risk function for predicting coronary heart disease in middle-aged and older adults.
Analyzed data from 1,025 men and 1,445 women aged 49 to 82 years free of coronary heart disease.
Utilized a risk function incorporating cholesterol levels, systolic blood pressure, left ventricular hypertrophy, and diabetes status.
Calculated CHD cases based on deciles of risk.
Less than 2% of CHD cases occurred in the lowest decile of risk.
25% of CHD cases in men and 37% in women were found in the highest decile of risk.
Predictability of CHD was confirmed for all specific age groups.

Structured PICO

Can a risk function based on lipids, blood pressure, LVH, and diabetes predict subsequent coronary heart disease in middle-aged and older persons?

Population

2,470 adults (1,025 men and 1,445 women), aged 49 to 82 years, free of coronary heart disease (CHD) at baseline.

Intervention

Risk function based on HDL and LDL cholesterol, systolic blood pressure, left ventricular hypertrophy, and diabetes

Outcome

Subsequent coronary heart disease (CHD)hard clinical

A risk function incorporating lipids, blood pressure, LVH, and diabetes effectively predicts coronary heart disease in middle-aged and older adults.

Cite This Study

Tavia Gordon (1977) studied this question.

synapsesocial.com/papers/69f29d0f1b51e2fbf01873c8 https://doi.org/10.1001/jama.1977.03280060041018

Topics

Women and heart disease

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Implication

Risk stratification by deciles concentrates most CHD events in highest-risk groups; supports prediction models but leaves open effects on clinical outcomes.

Predicting Coronary Heart Disease in Middle-Aged and Older Persons

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Predicting Coronary Heart Disease in Middle-Aged and Older Persons

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider