This review highlights the utility of multifactorial risk assessment algorithms, such as those derived from the Framingham Heart Study, to guide hypertension treatment based on absolute CHD risk.
Absolute CHD risk may guide hypertension therapy; leaves open need for randomized outcome trials before practice change.
Coronary heart disease (CHD) remains a major cause of morbidity and mortality in Western societies. Hypertension has been identified as a cardinal risk factor for CHD. Guidelines for hypertension classification and treatment are based on the results of clinical trials that have demonstrated reductions in cardiovascular endpoints in treated hypertensive patient. Controversy persists regarding the level of blood pressure at which treatment should be initiated and the desirable blood pressure goals of treatment. Several algorithms for CHD risk prediction have been developed. This report will review one recently developed approach for predicting CHD risk based upon observational data from the Framingham Heart Study. A rationale is presented for considering absolute level of CHD risk to guide hypertension treatment.
No takes yet. Share an insight, caveat, or question.
Daniel Levy (1993) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: