Why the study?
Does TVP1022 reduce infarct size and attenuate the decline in ventricular function in a rat model of ischaemia/reperfusion?
Population
Rat model of ischaemia/reperfusion, H9c2 cells, and neonatal rat ventricular myocytes exposed to oxidative…
Design
Preclinical
Follow-up
4 or 24 h reperfusion
Authors
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Hypothesis-generating in rat ischaemia/reperfusion; prospective human trials needed before clinical adoption.
Does TVP1022 reduce infarct size and attenuate the decline in ventricular function in a rat model of ischaemia/reperfusion?
TVP1022 demonstrated cardioprotective effects by reducing infarct size and preserving ventricular function in a rat model of ischaemia/reperfusion, suggesting potential as a novel adjunctive therapy.
Ertracht et al. (2011) studied this question.
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