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September 26, 2000Neurology

Carotid endarterectomy

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Why the study?

Does carotid endarterectomy reduce the risk of stroke in patients with carotid artery disease?

Population

Patients with carotid artery disease (symptomatic with 50-99% stenosis and asymptomatic individuals)

Design

Editorial

Authors

HBHenry J.M. BarnettBoston University
Joseph P. Broderick
Joseph P. BroderickBroad Institute

Discussion

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Overview

Supports targeted CEA in symptomatic high-grade stenosis; confirms trial benefit yet leaves asymptomatic thresholds open to re-evaluation.

Structured PICO

Does carotid endarterectomy reduce the risk of stroke in patients with carotid artery disease?

P
Population
Patients with carotid artery disease (symptomatic with 50-99% stenosis and asymptomatic individuals)
I
Intervention
Carotid endarterectomy
O
Outcome
Ipsilateral strokehard clinical

This editorial highlights the established benefits of carotid endarterectomy in carefully selected symptomatic and asymptomatic patients based on landmark trials.

Cite This Study

Barnett et al. (2000) studied this question.

synapsesocial.com/papers/6a7039b5e5469ee92be0fb0ehttps://doi.org/10.1212/wnl.55.6.746
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Beneficial Effect of Carotid Endarterectomy in Symptomatic Patients with High-Grade Carotid Stenosis1991 · 8,508 citations
  2. 2Benefit of Carotid Endarterectomy in Patients with Symptomatic Moderate or Severe Stenosis1998 · 3,623 citations
  3. 3Critical Appraisal of the Design and Reporting of Studies of Imaging and Measurement of Carotid Stenosis2000 · 105 citations
  4. 4Results of carotid endarterectomy with prospective neurologist follow-up2000 · 80 citations
  5. 5Stroke and mortality rate in carotid endarterectomy: 228 consecutive operations.1977 · 264 citations