Population
246 patients with carotid atherosclerotic plaques as evidenced by ultrasound
Design
Cross-sectional
Authors
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IL-6 measurement should not guide carotid plaque management; hypothesis-generating for inflammation-vulnerability link pending prospective validation.
Higher serum IL-6 levels are independently associated with lower echogenicity of carotid plaques, suggesting a link between systemic inflammation and plaque vulnerability.
Yamagami et al. (2004) studied this question.
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