Key result
Primary hyperaldosteronism is linked to altered body fluid and electrolyte composition versus normal controls.
Observational
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In a previous report, measurements of body fluid and electrolyte composition have been com- pared in normal subjects and patients with ar- terial hypertension (1). In this paper, similar studies are presented in a group of patients with primary hyperaldosteronism studied before and after surgical therapy and in a group of normal subjects given mineralocorticoid drugs. The re- stults indicate that the findings in the patients with established primary hyperaldosteronism differ
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Chobanian et al. (1961) conducted an observational in Primary hyperaldosteronism / Mineralocorticoid hypertension. Surgical therapy / Mineralocorticoid drugs vs. Pre-surgical baseline / Normal subjects was evaluated on Body fluid and electrolyte composition. Patients with established primary hyperaldosteronism showed differing body fluid and electrolyte composition compared to baseline or normal subjects.
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