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Design
Review
Guides site-specific nomenclature in pathology reports; leaves open standardization across institutions and specialties.
Note The fact that WD liposarcomas show no potential for metastasis unless they undergo dedifferentiation led in the late 1970s to the introduction of terms such as lipoma or lipomatous (ALT), particularly for lesions arising at surgically amenable locations in the limbs and trunk. Currently, lipomatous tumors and well-differentiated liposarcomas are synonyms describing lesions which are identical morphologically, karyotypically and in terms of biologic behavior. Use of each term is determined principally by the tumor's location; the term welldifferentiated liposarcoma is used almost exclusively for lesions in the retroperitoneum, while the term atypical lipomatous tumor is used for lesions arising elsewhere.
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Mavrogenis et al. (2013) studied this question.
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