Population
A large family group (kindred) with malignant hyperthermia susceptibility
Design
Other
Authors
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May support predictive testing in select malignant hyperthermia families; leaves open broader validation.
Genetic linkage analysis of the RYR1 gene can enable accurate predictive testing for malignant hyperthermia susceptibility in affected families even when known mutations are absent.
Wallace et al. (1996) studied this question.
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