In addition to six metabolites of oxycodone which were reported previously, 7 beta-hydroxy-6 beta-oxycodol was further isolated as one of the major metabolites in rabbits. The structure of this novel metabolite was characterized by mass and nuclear magnetic resonance spectra. Such a metabolite possessing vicinal hydroxyl groups in aliphatic ring is very new in the metabolism of narcotic analgesics.
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Ishida et al. (1982) studied this question.
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