Population
Bacterially expressed forms of NendoU of severe acute respiratory syndrome coronavirus and human coronavirus…
Design
Preclinical
Authors
Loading...
NendoU catalytic activity is essential for nidovirus replication; animal data leave open whether selective inhibitors can advance to human trials.
The study identifies NendoU as a critical endoribonuclease for coronavirus replication and transcription, serving as a major genetic marker for nidoviruses.
Ivanov et al. (2004) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: