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August 3, 2026Transplantation ProceedingsOpen Access

Profile of Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma at a Brazilian High-Complexity Referral Center: Tumor Biology as a Predictor of Post-Transplant Recurrence

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PMPedro Marin-CastroHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo RPRafael Soares PinheiroHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo DWDaniel Reis WaisbergUniversidade de São Paulo

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Implication

Retrospective analysis investigates post-transplant recurrence in patients with hepatocellular carcinoma, suggesting tumor biology plays a significant role.

Key Points

This study aims to analyze the clinical profile of patients undergoing liver transplantation for hepatocellular carcinoma and identify factors affecting survival and recurrence.
Retrospective study of patients who underwent liver transplantation for hepatocellular carcinoma between January 2015 and December 2024 at a Brazilian referral center.
Analysis included demographic data, MELD scores, locoregional therapy, and post-transplant outcomes.
Hepatocellular carcinoma was the cause of liver transplantation in 423 out of 1321 cases (32.02%).
Post-transplant HCC recurrence occurred in 34 patients (8.03%) with vascular invasion being the strongest predictor of recurrence.
The 5-year overall survival rate post-transplant was 74.6%, influenced by age, donor risk index, blood transfusions, and ICU stay.

Cite This Study

Marin-Castro et al. (2026) studied this question.

synapsesocial.com/papers/6a70402275942ff7265e4cc8 https://doi.org/10.1016/j.transproceed.2026.07.012

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Implication

Retrospective analysis investigates post-transplant recurrence in patients with hepatocellular carcinoma, suggesting tumor biology plays a significant role.

Profile of Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma at a Brazilian High-Complexity Referral Center: Tumor Biology as a Predictor of Post-Transplant Recurrence

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Cite This Study

Profile of Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma at a Brazilian High-Complexity Referral Center: Tumor Biology as a Predictor of Post-Transplant Recurrence

Discussion

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Implication

Key Points

Cite This Study

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