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August 3, 2026BMC PediatricsOpen Access

Neurodevelopmental sequelae in paediatric pneumococcal meningitis: a call for strengthened surveillance and follow-up care

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Authors

ATAngel Miraclin T.Christian Medical College, VelloreSOSamuel P. OommenChristian Medical College, VelloreSCSolomon D CruzChristian Medical College, Vellore

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Overview

Cross-sectional study reveals high long-term neurodevelopmental impacts of pneumococcal meningitis in children, stressing the need for better care.

Key Points

  • This study investigates the long-term neurodevelopmental outcomes in children following pneumococcal meningitis.
  • Cross-sectional design involving children with microbiologically confirmed pneumococcal meningitis from 2007 to 2022.
  • Structured neurodevelopmental screening and evaluations were conducted on survivors with parental consent.
  • Data were analyzed for clinical, laboratory, and neurological outcomes.
  • The in-hospital case fatality rate was 10.4%; 25.7% of survivors died post-discharge.
  • Only 57.2% of children achieved favourable outcomes (mRS 0–2), with 17.2% experiencing moderate-to-severe disability.
  • High rates of long-term sequelae included learning difficulties (54.2%) and intellectual disability (37.5%).

Cite This Study

T. et al. (2026) studied this question.

synapsesocial.com/papers/6a70406d75942ff7265e5660https://doi.org/10.1186/s12887-026-07438-6
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