Resistant hypertension has a prevalence of 10% among treated hypertensive patients, with a high rate (27.6%) of white-coat effect, highlighting the importance of home and standing BP measurements.
Underscores value of home and standing BP measurements in treated hypertension; leaves open prospective validation of risk factors for true resistant hypertension.
We assessed prevalence and clinical characteristics of resistant hypertension (RH) and prevalence of false RH (white-coat effect [WCE] by home blood pressure [BP] monitoring), among a population of 302 treated hypertensive patients, mean age 66.6 (± 13.8), 67.5% women. Resistant hypertension was defined according to the American Heart Association criteria. Prevalence of RH was 10%, and the following five variables were independently associated with it: body mass index, diabetes, isolated systolic hypertension, orthostatic hypotension, and use of beta-blockers. Prevalence of WCE among subjects with office-RH was 27.6%. Our study identified easily measurable parameters related to RH. Standing BP should be systematically measured in individuals with RH.
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Barochiner et al. (2012) studied this question.
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