What question did this study set out to answer?

To determine the prevalence of preventive aspirin use in older US adults with and without diabetes based on age, sex, and cardiovascular disease risk.

June 21, 2021JAMA Network OpenOpen Access

Use of Preventive Aspirin Among Older US Adults With and Without Diabetes

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Why the study?

The net benefit of preventive aspirin remains debated, and potential harms may outweigh benefits in older adults, highlighting the need to monitor current use.

What is the prevalence of preventive aspirin use among older US adults with and without diabetes?

Population

7103 individuals 60 years or older with and without diabetes in the US

Comparison

Older adults with diabetes vs without diabetes

Design

Cross-sectional analysis of nationally representative NHANES survey data

Authors

ELElizabeth Y. LiuJohns Hopkins University MAMohammed E. Al‐SofianiSaudi Electronic University HYHsin‐Chieh YehJohns Hopkins University

Discussion

Member takes

Implication

Higher aspirin use among older adults with diabetes signals potential overprescribing risk; leaves open targeted deprescribing trials.

Key Points

To determine the prevalence of preventive aspirin use in older US adults with and without diabetes based on age, sex, and cardiovascular disease risk.
Cross-sectional analysis using national data from the National Health and Nutrition Examination Survey 2011-2018
7103 individuals aged 60 years or older completed a questionnaire about aspirin use
Statistical analyses conducted from July 1, 2019, to April 1, 2021.
61.7% of older adults with diabetes use aspirin compared to 42.2% without diabetes
Aspirin use for primary prevention is higher in older vs younger age categories among those without diabetes (OR 1.50; 95% CI 1.23-1.83 for 70-79 years)
9.9 million older US adults report aspirin use for primary prevention, yet many may not benefit from continued use.

Structured PICO

What is the prevalence of preventive aspirin use among older US adults with and without diabetes?

Population

7103 US adults aged 60 years or older with and without diabetes, mean age 69.6, 45.2% men, 75.8% White participants.

Intervention

Preventive aspirin use (self-reported low-dose aspirin therapy based on physician's advice or own decision)

Outcome

Prevalence of preventive aspirin use for primary and secondary prevention by age, sex, and CVD risk category

A large proportion of older US adults, particularly those with diabetes, continue to use aspirin for primary prevention despite recent evidence suggesting potential harm outweighs benefits in this population.

Cite This Study

Liu et al. (2021) studied this question.

synapsesocial.com/papers/6a70468f87f9210571279304 https://doi.org/10.1001/jamanetworkopen.2021.12210

Topics

Cardiovascular prevention Women and heart disease

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Use of Preventive Aspirin Among Older US Adults With and Without Diabetes

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Use of Preventive Aspirin Among Older US Adults With and Without Diabetes

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider