Why the study?
Does myocardial perfusion imaging improve the detection of myocardial infarction or significant coronary disease compared to serial cardiac troponin I in emergency department patients with chest pain at low to moderate risk for ACS?
Does myocardial perfusion imaging improve the detection of myocardial infarction or significant coronary disease compared to serial cardiac troponin I in emergency department patients with chest pain at low to moderate risk for ACS?
Early myocardial perfusion imaging and serial cardiac troponin I provide complementary information, with comparable sensitivity for identifying myocardial infarction, but perfusion imaging offers higher sensitivity and lower specificity for identifying significant coronary disease or need for revascularization.
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May complement serial troponin for coronary disease detection; leaves open whether routine perfusion imaging improves outcomes in low-moderate risk chest pain.
Kontos et al. (1999) studied this question.
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