Population
Visna virus 1514 genome and LV1-1 antigenic variant
Design
Preclinical
Authors
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Animal data on visna env variability; leaves open applicability to HIV antigenic variation in patients.
The study identifies a hypervariable site in the visna virus env gene that correlates with a lack of RNA secondary structure, similar to HIV, providing insights into lentivirus evolution and antigenic variation.
Braun et al. (1987) studied this question.
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