What question did this study set out to answer?

The study aims to examine the incidence, prognosis, and risk factors associated with ventricular arrhythmias in men, differentiating between those with and without cardiovascular disease.

October 1, 1999Journal of Internal MedicineOpen Access

Ventricular arrhythmias during 24‐h ambulatory ECG recording: incidence, risk factors and prognosis in men with and without a history of cardiovascular disease

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Why the study?

Does the presence of frequent or complex ventricular arrhythmias on 24-h ambulatory ECG predict mortality and cardiac events in 68-year-old men with and without cardiovascular disease?

Population

443 randomly selected 68-year-old men with and without a history of cardiovascular disease or asymptomatic…

Comparison

Presence of frequent or complex ventricular… vs Absence of frequent or complex ventricular…

Design

Cohort

Follow-up

11 years

Authors

GEGunnar EngströmPreventive Cardiology BHBo HedbladBroad Institute LJLars JanzonGeneral / Preventive / Lipids

Discussion

Member takes

Implication

May refine prognosis via ambulatory ECG in older men with CVD; leaves open whether detection guides interventions.

Key Points

The study aims to examine the incidence, prognosis, and risk factors associated with ventricular arrhythmias in men, differentiating between those with and without cardiovascular disease.
Prospective cohort study with 443 randomly selected 68-year-old men over 11 years of follow-up.
Subjects underwent 24-hour ambulatory electrocardiographic (ECG) monitoring and non-invasive cardiovascular assessments.
Mortality and cardiac events were tracked during the study period.
Frequent or complex arrhythmias were prevalent in men with cardiovascular disease, linked to increased cardiac event rates (P = 0.001) and mortality (P = 0.054).
Men with angina or prior myocardial infarction had the highest incidence of arrhythmias and poorest prognoses.
Smoking and diabetes mellitus were notable independent factors for frequent arrhythmias in men with cardiovascular disease.

Structured PICO

Does the presence of frequent or complex ventricular arrhythmias on 24-h ambulatory ECG predict mortality and cardiac events in 68-year-old men with and without cardiovascular disease?

Population

443 randomly selected 68-year-old men with and without a history of cardiovascular disease (CVD) or asymptomatic non-invasively detected CVD

Intervention

Presence of frequent or complex ventricular arrhythmias (Lown class 2-5) detected on 24-h ambulatory ECG recording

Comparator

Absence of frequent or complex ventricular arrhythmias

Outcome

Mortality and cardiac event rates during an 11-year periodhard clinical

Frequent or complex ventricular arrhythmias on 24-hour ambulatory ECG predict increased cardiac events and mortality in men with cardiovascular disease, but not in those without.

Cite This Study

Engström et al. (1999) studied this question.

synapsesocial.com/papers/6a7051905671bbf00bc2b025 https://doi.org/10.1046/j.1365-2796.1999.00509.x

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Ventricular arrhythmias during 24‐h ambulatory ECG recording: incidence, risk factors and prognosis in men with and without a history of cardiovascular disease

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Ventricular arrhythmias during 24‐h ambulatory ECG recording: incidence, risk factors and prognosis in men with and without a history of cardiovascular disease

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider