Why the study?
It was unclear whether left atrial fibrosis is an independent determinant of atrial fibrillation in patients with mitral stenosis who underwent balloon mitral valvotomy.
Is left atrial fibrosis an independent determinant of atrial fibrillation in patients with mitral stenosis?
Is left atrial fibrosis an independent determinant of atrial fibrillation in patients with mitral stenosis?
Left atrial fibrosis assessed by MRI does not appear to be an independent determinant of atrial fibrillation in patients with mitral stenosis, whereas left atrial enlargement is significantly associated.
LA fibrosis was associated with AF in mitral stenosis; leaves open its role as a determinant post-valvotomy.
We prospectively studied whether left atrial (LA) fibrosis is a determinant of atrial fibrillation (AF) in mitral stenosis in patients who underwent balloon mitral valvotomy. There were 2 groups: Group A (n = 16), with AF and Group B (n = 27), without AF. Fibrosis was assessed by MRI. Patients underwent cardioversion before MRI. There were 27 females and 16 males, aged 29 ± 6 years. The LA areas in Groups A and B were 54.3 ± 4.4 mm2 and 39.4 ± 2.3 mm2 (p < 0.05) and the LA volume index was 46.2 ± 2.9 ml/m2 vs 33 ± 3 ml/m2 respectively (p < 0.0001). The presence of LA scarring was not statistically different in the two groups.
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Pawar et al. (2021) studied this question.
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