Histoplasmosis in Infancy

The disease histoplasmosis, which was first described by Darling in 1906 and 1908,¹has since been observed and reported many times. An able review by Meleney²appeared in 1940. Since this review and summary of 32 cases, 5 additional ones, 3 of infants³and 2 of adults,⁴have been reported, making the total number of cases 37. In 7 of these⁵the patients have been infants less than 15 months of age. Dodd and Tompkins5awere able to make the diagnosis of the disease in an infant before death. The other patients with diagnoses made during life⁶were adults. The patient here described is the eighth infant to be reported on and the second one in whose case a diagnosis of histoplasmosis was made before death. REPORT OF A CASE The patient, a white girl, was born on Oct. 29, 1940, at full term, by normal delivery. An evaporated milk