Population
9 Björk-Shiley aortic prostheses recovered six months or longer after implantation, and in vitro models
Design
Case_series
Follow-up
6 months or longer
Authors
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Supports flow-mediated thrombosis in mechanical valves; hypothesis-generating for hemodynamic optimization in future designs.
Thrombus formation and tissue overgrowth on the Björk-Shiley aortic prosthesis are likely driven by a stagnation zone and low shear stress in the minor outflow region.
Yoganathan et al. (1978) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: