Why the study?
Although cardiovascular health is recognized to affect cognition, the association between orthostatic hypotension and cognition remains unclear.
Is orthostatic hypotension associated with cognitive impairment and incident cognitive decline in older women not taking antihypertensive drugs?
Is orthostatic hypotension associated with cognitive impairment and incident cognitive decline in older women not taking antihypertensive drugs?
In older women not on antihypertensive therapy, systolic blood pressure drop upon standing is associated with baseline cognitive impairment, but orthostatic hypotension per se does not predict incident cognitive decline.
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SBP drop on standing was associated with baseline cognitive impairment in older women; leaves open whether OH predicts incident decline.
Duval et al. (2023) studied this question.
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