Why the study?
Although morphine is widely used for acute pulmonary oedema and dyspnoea relief, retrospective studies have raised concerns regarding its safety and efficacy in acute heart failure.
Does morphine improve outcomes or pose risks in patients with acute heart failure?
Does morphine improve outcomes or pose risks in patients with acute heart failure?
This review highlights emerging concerns from observational studies regarding the safety and efficacy of morphine, traditionally considered standard therapy for acute heart failure.
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Morphine use in acute heart failure warrants caution from observational data; leaves open need for randomized trials to clarify net benefit.
Caspi et al. (2020) studied this question.
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