May 1, 1983Pacing and Clinical Electrophysiology

The Electrophysiologic Basis for the Use of Amiodarone for Treatment of Cardiac Arrhythmias

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Population

Isolated cardiac tissues, whole animal, and human studies

Design

Review

Authors

AHAngas HamerBox Hill Hospital WMWilliam J. MandelElectrophysiology CZCarol ZaherUniversity of California, Los Angeles

Discussion

Member takes

Implication

Supports arrhythmia management decisions; leaves open updated correlations with modern comorbidities and dosing.

Structured PICO

Population

Isolated cardiac tissues, whole animal, and human studies

Intervention

Amiodarone (oral and intravenous)

Amiodarone's broad efficacy in treating cardiac arrhythmias is based on its ability to prolong action potential duration and refractory periods across cardiac tissues, with a time-dependent mechanism of action.

Cite This Study

Hamer et al. (1983) studied this question.

synapsesocial.com/papers/6a7055c2febe604dd7092052 https://doi.org/10.1111/j.1540-8159.1983.tb05340.x

View Full Paper

Ask AI

Bookmark

The Electrophysiologic Basis for the Use of Amiodarone for Treatment of Cardiac Arrhythmias

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The Electrophysiologic Basis for the Use of Amiodarone for Treatment of Cardiac Arrhythmias

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider