Key result
Black patients with angioedema were significantly more likely to have an ACEI as the inciting agent compared to other patient groups (70% vs 44%; OR 3.03, 95% CI 1.54-5.94).
Why the study?
Are black patients at a higher risk for ACEI-induced angioedema compared to other demographic groups?
Population
182 patients with angioedema treated at a tertiary care hospital from 1999 to 2004.
Comparison
Angiotensin-converting enzyme inhibitors (ACEI) vs Non-black patient groups
Design
Cohort
Authors
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Supports targeted ACEI angioedema monitoring in Black patients; hypothesis-generating for race-specific risk tools.
Observational (n=182)
No
Are black patients at a higher risk for ACEI-induced angioedema compared to other demographic groups?
Odds Ratio: 3.03 (95% CI 1.54–5.94)
Absolute Event Rate: 70% vs 44%
Black patients have a significantly higher risk of developing ACE inhibitor-induced angioedema compared to other demographic groups.
Mahoney et al. (2008) conducted an observational in Angioedema (n=182). Black race vs. Other patient groups was evaluated on ACEI as the inciting agent for angioedema (OR 3.03, 95% CI 1.54-5.94). Black patients with angioedema were significantly more likely to have an ACEI as the inciting agent compared to other patient groups (70% vs 44%; OR 3.03, 95% CI 1.54-5.94).
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