Key result
Multiple risk factors were associated with acute kidney injury after cardiovascular surgery, most notably cardiopulmonary bypass time (OR 33.78; 95% CI 23.15-44.41) and aortic clamping time.
Why the study?
What are the preoperative, intraoperative, and postoperative risk factors for acute kidney injury after cardiovascular surgery?
Population
51,934 patients from 14 case-control studies who underwent cardiovascular surgery with cardiopulmonary…
Design
Meta-analysis
Authors
Loading...
Prolonged bypass and clamp times strongly predict post-cardiac surgery AKI; extends evidence for intraoperative time minimization in prevention trials.
Meta-Analysis (n=51,934)
What are the preoperative, intraoperative, and postoperative risk factors for acute kidney injury after cardiovascular surgery?
Odds Ratio: 33.78 (95% CI 23.15–44.41)
Multiple preoperative, intraoperative, and postoperative factors, particularly prolonged cardiopulmonary bypass and aortic clamping times, significantly increase the risk of acute kidney injury following cardiovascular surgery.
Qian et al. (2016) conducted a meta-analysis in Cardiovascular surgery-associated acute kidney injury (AKI-CS) (n=51,934). Preoperative, intraoperative, and postoperative risk factors (e.g., cardiopulmonary bypass time) vs. Patients without the respective risk factors was evaluated on Acute kidney injury after cardiovascular surgery (AKI-CS) (OR 33.78, 95% CI 23.15-44.41). Multiple risk factors were associated with acute kidney injury after cardiovascular surgery, most notably cardiopulmonary bypass time (OR 33.78; 95% CI 23.15-44.41) and aortic clamping time.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: