Key result
Mobile app-based self-management lowers cholesterol by ~17 mg/dL vs conventional care in CAD.
Why the study?
Although medications can improve lipid profiles in coronary artery disease, levels often remain above targets, making mobile self-management programs crucial for lipid control and secondary prevention.
Does a mobile application-based self-management program reduce cholesterol, triglyceride, and low-density lipoprotein levels in adults with coronary artery disease?
RCT (n=48)
Open-label
Permuted blocks of four
No
Does a mobile application-based self-management program reduce cholesterol, triglyceride, and low-density lipoprotein levels in adults with coronary artery disease?
Standardized Mean Difference: 0.61 (95% CI 0.03–1.18)
Absolute Event Rate: 144.11% vs 160.67%
p-value: p=0.039
A mobile application-based self-management program significantly improves short-term lipid profiles in patients with coronary artery disease when compared to conventional care alone.
May support mobile app self-management as lipid-lowering adjunct in CAD; extends short-term RCT evidence for digital self-management tools.
Background: Cholesterol, triglycerides, and low-density lipoprotein levels are key indicators of patients’ self-care in coronary artery disease; although medications can improve lipid profiles, the results often remain above targets. Implementing mobile self-management programs is crucial for reducing the incidence of coronary artery disease, preventing cardiac events, and enhancing well-being. Objective: This study aimed to evaluate the impact of a self-management program on cholesterol, triglycerides, and low-density lipoprotein levels in people with coronary artery disease. Methods: A randomized controlled trial design was employed at a tertiary hospital in Thailand between June 2022 and June 2023. Forty-eight people were randomly assigned to one of two groups: control or experimental. The experimental group used applications and the telephone for four weeks to self-manage cholesterol, triglyceride, and low-density lipoprotein levels, while the control group received conventional care. Data were gathered about cholesterol, triglyceride, and low-density lipoprotein levels. Descriptive statistics, independent t-tests, and dependent t-tests were employed to analyze between-group and within-group differences. Effect sizes (Cohen’s d) with 95% confidence intervals were calculated. Results: Results showed that the experimental group had a statistically significant reduction in cholesterol (t = 2.121, df = 46, p = 0.039), triglyceride (t = 2.060, df= 46, p = 0.046), and low-density lipoprotein levels (t = 2.115, df = 46, p = 0.040) compared to the control group. This study demonstrates that a mobile application self-management program can lower lipid levels. Conclusions: The findings indicate that a mobile application–based self-management program can significantly reduce cholesterol, triglyceride, and low-density lipoprotein levels in people with coronary artery disease in the short term. These findings highlight the crucial role of nurses applying these strategies to enhance patient care.
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Polsook et al. (2026) conducted an RCT in Coronary artery disease (n=48). Mobile application-based self-management program vs. Conventional care was evaluated on Cholesterol level at 3 months (mg/dL) (Cohen's d 0.61, 95% CI 0.03-1.18, p=0.039). A 4-week mobile application-based self-management program significantly reduced cholesterol (Cohen's d 0.61), triglycerides, and LDL levels compared to conventional care in coronary artery disease.
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