Why the study?
Does decaffeinated coffee reduce blood pressure compared to regular coffee in healthy adults with habitual coffee intake?
Population
45 healthy normotensive volunteers with a habitual intake of 4-6 cups coffee/day.
Comparison
5 cups of decaffeinated coffee each day for a… vs 5 cups of regular coffee each day for a period…
Design
RCT, randomized crossover, double-blind
Follow-up
12 weeks (6 weeks per crossover period)
Authors
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Small BP reductions with decaffeinated coffee substitution unlikely to change practice; provides RCT confirmation of caffeine's ambulatory effects.
Does decaffeinated coffee reduce blood pressure compared to regular coffee in healthy adults with habitual coffee intake?
Replacing regular coffee with decaffeinated coffee leads to a statistically significant but clinically small reduction in blood pressure in healthy, normotensive adults.
Dusseldorp et al. (1989) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: