Key result
Cryoballoon ablation is equivalent to radiofrequency ablation with respect to efficacy for the treatment of patients with paroxysmal atrial fibrillation.
Should not yet change ablation choice in paroxysmal AF; leaves open need for randomized confirmation of equivalence.
Atrial brillation (AF), as one of the most common cardiac arrhythmias, is associated with significant morbidity and mortality (1). Pulmonary vein isolation (PVI) remains the cornerstone treatment for paroxysmal atrial fibrillation (PAF) (2). The second generation of cryoballoon (CB2, Arctic Front Advance, Medtronic, Inc., MN, USA) has proven high success rate in PVI for patients with PAF (3,4). The “Fire and Ice trial” confirms cryoballoon ablation is equivalent to radiofrequency ablation with respect to ef cacy for the treatment of patients with PAF (5).
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Lin et al. (2018) conducted a review in paroxysmal atrial fibrillation (PAF). cryoballoon ablation vs. radiofrequency ablation was evaluated. Cryoballoon ablation is equivalent to radiofrequency ablation with respect to efficacy for the treatment of patients with paroxysmal atrial fibrillation.
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