What is the clinical evidence from this study?

Study design: Editorial. Population: Healthy adults (n=3839). Intervention: Female sex vs. Male sex. Primary outcome: SBP/Watt slope (p=<0.001).

April 11, 2020European Journal of Preventive CardiologyOpen Access

Rays of light into the ‘black-box’ of exercise hypertension

Q: What are the key findings of this study?

Workload-indexed systolic blood pressure response during bicycle ergometry was markedly higher in women than in men (SBP/Watt slope: 0.52 vs. 0.41 mmHg/Watt; P<0.001).

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Key result

Workload-indexed systolic blood pressure response during bicycle ergometry was markedly higher in women than in men (SBP/Watt slope: 0.52 vs. 0.41 mmHg/Watt; P<0.001).

Population

3,839 healthy adult subjects, with a wide range of ages and free from cardiovascular disease and risk factors.

Design

Editorial

Authors

BBBirna Bjarnason‐WehrensPreventive Cardiology HPHans‐Georg PredelGerman Sport University Cologne

Discussion

Member takes

Implication

This editorial highlights a study providing the first normative reference values for workload-indexed systolic blood pressure response during bicycle ergometry, revealing significantly higher responses in women compared to men.

Structured PICO

Population

3,839 healthy adult subjects free from cardiovascular disease and risk factors, evaluated for workload-indexed systolic blood pressure response during bicycle ergometry.

Exposure

Bicycle ergometer exercise testing using an individualised ramp protocol (beginning with 20–100 Watt; continuous ramp 10/15 or 20 Watt/minute; total exercise time 8–12 minutes; until exhaustion) with exercise systolic blood pressure measured every 2–3 minutes.

Outcome

Age and sex-specific upper limits and reference equations for the workload-indexed systolic blood pressure response (SBP/Watt slope and peak SBP/Watt ratio).surrogate

Main Result

Absolute Event Rate: 0.52% vs 0.41%

p-value: p=<0.001

Limitations

Findings are only valid for the specific test protocol used in the study.
The test protocols were highly individualized, which considerably limits transfer into general clinical routine.
Findings obtained are only valid for the test protocol used in the study.
Test protocols in the study are highly individualised, which considerably limits the transfer into the general clinical routine.

Cite This Study

Bjarnason‐Wehrens et al. (2020) conducted an editorial in Healthy adults (n=3,839). Female sex vs. Male sex was evaluated on SBP/Watt slope (p=<0.001). Workload-indexed systolic blood pressure response during bicycle ergometry was markedly higher in women than in men (SBP/Watt slope: 0.52 vs. 0.41 mmHg/Watt; P<0.001).

synapsesocial.com/papers/6a705f3135aa2c282ce1ae0f https://doi.org/10.1177/2047487320918343

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Rays of light into the ‘black-box’ of exercise hypertension

Discussion

Member takes

Implication

Structured PICO

Main Result

Limitations

Cite This Study

Rays of light into the ‘black-box’ of exercise hypertension

Discussion

Member takes

Implication

Structured PICO

Main Result

Limitations

Cite This Study

Also Consider

Also Consider