What question did this study set out to answer?

To evaluate how infarct artery perfusion and collateral vessels affect the relationship between initial peak ST-segment elevation and final electrocardiographic infarct size.

September 1, 1986HeartOpen Access

Influence of infarct artery patency on the relation between initial ST segment elevation and final infarct size.

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Why the study?

Does infarct artery patency alter the relationship between initial ST segment elevation and final infarct size in patients with acute myocardial infarction?

Population

37 patients with acute myocardial infarction

Comparison

Infarct artery patency vs Persistently occluded infarct artery without…

Design

Cohort

Authors

RHRosemary A. HackworthyJohn Hunter Hospital MVM VogelRoyal Prince Alfred Hospital PHPhillip J. HarrisRoyal Prince Alfred Hospital

Discussion

Member takes

Implication

Initial ST elevation may overestimate infarct size with reperfusion or collaterals; leaves open its utility for risk stratification in AMI.

Key Points

To evaluate how infarct artery perfusion and collateral vessels affect the relationship between initial peak ST-segment elevation and final electrocardiographic infarct size.
Assessed 37 patients presenting with acute myocardial infarction for coronary patency and collateral flow.
Measured initial peak ST-segment elevations across leads and compared them to final electrocardiographic infarct sizes.
Initial peak ST elevation correlated with final infarct size in patients with anterior infarction and complete occlusion lacking collateral vessels.
Final infarct size was smaller than predicted from initial ST elevation in patients with subtotal occlusion and in all inferior infarctions (8 of 10 having collaterals).

Structured PICO

Does infarct artery patency alter the relationship between initial ST segment elevation and final infarct size in patients with acute myocardial infarction?

Population

37 patients with acute myocardial infarction

Intervention

Infarct artery patency (spontaneous reperfusion by anterograde flow or via collaterals)

Comparator

Persistently occluded infarct artery without collaterals

Outcome

Final electrocardiographic infarct size relative to initial ST segment elevationsurrogate

Spontaneous reperfusion by anterograde flow or via collaterals may salvage jeopardized myocardium, altering the relationship between initial ST elevation and final infarct size.

Cite This Study

Hackworthy et al. (1986) studied this question.

synapsesocial.com/papers/6a705fc526770c2b8de07e00 https://doi.org/10.1136/hrt.56.3.222

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Implication

Initial ST elevation may overestimate infarct size with reperfusion or collaterals; leaves open its utility for risk stratification in AMI.

Influence of infarct artery patency on the relation between initial ST segment elevation and final infarct size.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Influence of infarct artery patency on the relation between initial ST segment elevation and final infarct size.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider