Population
Open-chest anesthetized dogs with heart rate maintained at 140 beats/min by left atrial pacing
Comparison
Dilazep (50 micrograms/kg, i.v.) vs Baseline state
Design
Preclinical
Authors
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These animal data should not alter clinical practice; leaves open translation of systolic microvascular velocity patterns to human coronary perfusion.
The phasic blood flow pattern in subepimyocardial microvessels differs markedly from large epicardial arteries, with peak velocities occurring during systole.
Ashikawa et al. (1986) studied this question.
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