Key result
Taurus Trio TAVR resolves post-LVAD aortic regurgitation without valve migration at 1 month.
Why the study?
Aortic regurgitation occurs in 25%-30% of patients within the first year after LVAD implantation, but there is no clinical guideline consensus regarding the optimal treatment approach.
Case Report (n=1)
No
Transfemoral TAVR using a dedicated valve with locators (Taurus Trio) offers a feasible and effective minimally invasive treatment for patients with severe aortic regurgitation post-LVAD.
Supports feasibility of Taurus Trio TAVR for post-LVAD AR; leaves open durability, safety, and generalizability.
Background: Approximately 25%-30% of patients experience aortic regurgitation (AR) within the first year after left ventricular assist device (LVAD) implantation. However, there is currently no consensus in clinical guidelines regarding the optimal treatment approach for LVAD-associated AR. Case summary: We report a case of a female patient who developed AR following LVAD implantation. This patient exhibited an open-like configuration of left ventricular outflow tract (LVOT), with no calcified stenosis in the supravalvular region and a lack of anchoring anatomical structures at the junction of the LVOT and sinus-tubular junction. This anatomical configuration posed a high risk of prosthetic valve displacement during conventional transcatheter aortic valve replacement (TAVR). Therefore, we employed a novel TAVR system (Taurus Trio) equipped with a locator, which effectively prevented downward migration of the prosthetic valve after implantation. Discussion: This case indicates the potential advantages and efficacy of the Taurus Trio valve in TAVR for AR Post-LVAD. We plan to conduct long-term follow-up to further explore and optimize the treatment protocol.
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Cheng et al. (2025) conducted a case report in Aortic regurgitation post-LVAD (n=1). Transcatheter aortic valve replacement (Taurus Trio valve) was evaluated on Resolution of aortic regurgitation and valve stability. Transfemoral transcatheter aortic valve replacement using the Taurus Trio valve successfully resolved post-LVAD aortic regurgitation without valve migration at 1-month follow-up.
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