Key result
General practitioners were significantly less likely to start antihypertensive treatment in frail oldest-old patients compared to non-frail patients (OR 0.53), independent of systolic blood pressure and cardiovascular disease.
Cross-Sectional (n=2,543)
Yes
Odds Ratio: 0.53 (95% CI 0.48–0.59)
Across 29 countries, GPs are significantly less likely to initiate antihypertensive treatment in frail oldest-old patients, highlighting a critical need for clinical trials and guidelines specifically addressing this vulnerable population.
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May support frailty-informed prescribing caution in oldest-old; leaves open need for trials on outcome impact.
Streit et al. (2017) conducted a cross-sectional in Hypertension in oldest-old patients (n=2,543). Frailty in oldest-old patients vs. Non-frail oldest-old patients was evaluated on GP's decision to start antihypertensive treatment (OR 0.53, 95% CI 0.48-0.59). General practitioners were significantly less likely to start antihypertensive treatment in frail oldest-old patients compared to non-frail patients (OR 0.53), independent of systolic blood pressure and cardiovascular disease.
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