Key result
This review evaluates the current literature and clinical data on transcatheter aortic valve implantation to determine its applicability in lower-risk patients with severe aortic stenosis.
Why the study?
Does transcatheter aortic valve implantation (TAVI) benefit lower risk patients with severe aortic stenosis?
Does transcatheter aortic valve implantation (TAVI) benefit lower risk patients with severe aortic stenosis?
This review explores the potential expansion of TAVI indications to lower-risk patients with severe aortic stenosis.
TAVI expansion to lower-risk severe AS not yet warranted; leaves open need for dedicated RCTs.
Patients with severe aortic stenosis are sometimes not candidates for conventional open heart surgery because of severe deconditioning, excessive risk factors, and multiple comorbidities. Transcatheter aortic valve implantation (TAVI) is a relatively recent intervention, which was initially addressed to individuals with severe symptomatic aortic stenosis at substantial or prohibitive surgical risk. Despite the documented beneficial effects of this therapeutic intervention in certain carefully selected individuals, it has not yet been applied to lower risk patients. This is a review of the current literature and accumulated clinical data of this rapidly evolving invasive procedure in an attempt to resolve whether it can now be applied to a wider portion of patients with aortic stenosis.
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Panayiotides et al. (2014) conducted a review in Severe aortic stenosis. Transcatheter aortic valve implantation (TAVI) was evaluated. This review evaluates the current literature and clinical data on transcatheter aortic valve implantation to determine its applicability in lower-risk patients with severe aortic stenosis.
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