Key result
Genetic characterization of foot-and-mouth disease outbreaks in Algeria in 2017 revealed the A/AFRICA/G-IV lineage, closely related to Nigerian strains, marking its first report there since 1977.
The study identifies the A/AFRICA/G-IV lineage as the cause of 2017 FMD outbreaks in Algeria, marking the first clinical cases due to this serotype in the country since 1977.
Alerts to FMD re-emergence risk in North Africa; leaves open transmission routes for targeted surveillance studies.
This study describes the genetic characterization of serotype A viruses collected during outbreaks of foot-and-mouth disease (FMD) that occurred in Algeria in 2017. These are the first reports of clinical cases due to this serotype in the country since 1977. One complete genomic sequence (comprising 8,119 nucleotides) and three additional near-complete genomic sequences were generated. Phylogenetic analyses demonstrated that these viruses were classified within the A/AFRICA/G-IV lineage, most closely related to viruses circulating in Nigeria between 2009 and 2015. These unexpected results motivate further studies to define the precise pathways by which this viral lineage has been introduced into North Africa in order to understand risks of future disease incursions into the region.
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Pezzoni et al. (2018) studied Foot-and-mouth disease. A/AFRICA/G-IV lineage was evaluated on Genetic characterization and phylogenetic classification. Genetic characterization of foot-and-mouth disease outbreaks in Algeria in 2017 revealed the A/AFRICA/G-IV lineage, closely related to Nigerian strains, marking its first report there since 1977.
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