Key result
The 2015-2016 foot-and-mouth disease outbreaks in the Middle East were caused by the A/ASIA/G-VII virus lineage originating from the Indian subcontinent, with an estimated mutation rate of 1.1 × 10^-2 nt/site/y.
Population
101 serotype A foot-and-mouth disease virus G-VII VP1 sequences, including 57 strains isolated from cattle…
Design
Other
Authors
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May warrant enhanced surveillance for A/ASIA/G-VII; leaves open optimal control strategies in the Middle East.
Observational (n=101)
Effect estimate: 1.1 × 10^-2 nt/site/y (95% CI 8.0 × 10^-3 to 1.4 × 10^-2)
The emergence of the A/ASIA/G-VII lineage of foot-and-mouth disease virus in the Middle East involved multiple introductions and rapid antigenic evolution, potentially driven by intensive vaccination programs.
Bachanek‐Bankowska et al. (2018) conducted an observational in Foot-and-Mouth Disease (n=101). A/ASIA/G-VII virus lineage was evaluated on Evolutionary mutation rate of the G-VII C clade lineage (1.1 × 10^-2 nt/site/y, 95% CI 8.0 × 10^-3 to 1.4 × 10^-2). The 2015-2016 foot-and-mouth disease outbreaks in the Middle East were caused by the A/ASIA/G-VII virus lineage originating from the Indian subcontinent, with an estimated mutation rate of 1.1 × 10^-2 nt/site/y.
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