Why the study?
Does ultrafilterable platinum concentration predict cisplatin-induced renal dysfunction in cancer patients?
Does ultrafilterable platinum concentration predict cisplatin-induced renal dysfunction in cancer patients?
Ultrafilterable platinum concentration measured 16 hours after cisplatin administration may help identify patients at risk for cisplatin-induced renal dysfunction.
UF platinum was associated with cisplatin-induced creatinine clearance decline; hypothesis-generating for risk prediction and requires prospective validation.
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Lagrange et al. (1997) studied this question.
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