Why the study?
Does myocardial infarction induce reexpression of T-type Ca2+ channel gene and current in remodeled rat left ventricle?
Population
Neonatal rat left ventricle, adult sham-operated left ventricle, and remodeled hypertrophied left ventricle…
Comparison
Myocardial infarction (MI) model vs Sham-operated adult rats and neonatal rats
Design
Preclinical
Follow-up
3 to 4 weeks post-myocardial infarction
Authors
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May warrant exploration of T-type Ca2+ blockade in post-MI remodeling; leaves open translation from rat to human ventricle.
Does myocardial infarction induce reexpression of T-type Ca2+ channel gene and current in remodeled rat left ventricle?
T-type Ca2+ channel gene and current are reexpressed in post-myocardial infarction remodeled left ventricular myocytes in rats.
Ben Huang (2000) studied this question.
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