Key result
Pulmonary thromboendarterectomy significantly reduced mean pulmonary artery pressure from 59 mm Hg to 24 mm Hg intraoperatively (p<0.001), with no early postoperative mortality.
Why the study?
The study analyzed central hemodynamic parameters, incidence of residual pulmonary hypertension, complications, and functional status in the early postoperative period after pulmonary thromboendarterectomy.
Does pulmonary thromboendarterectomy improve central hemodynamic parameters in patients with chronic thromboembolic pulmonary hypertension?
Cohort (n=42)
Does pulmonary thromboendarterectomy improve central hemodynamic parameters in patients with chronic thromboembolic pulmonary hypertension?
Absolute Event Rate: 24% vs 59%
p-value: p=<0.001
Pulmonary thromboendarterectomy significantly improves central hemodynamics and functional status in patients with chronic thromboembolic pulmonary hypertension in the early postoperative period, with low mortality.
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Small single-center PTE series in CTEPH leaves open durability of early hemodynamic gains and RPH effects; larger prospective studies required.
Осадчий et al. (2024) conducted a cohort in chronic thromboembolic pulmonary hypertension (n=42). Pulmonary thromboendarterectomy vs. Baseline was evaluated on Mean pulmonary artery pressure (PAP) (p=<0.001). Pulmonary thromboendarterectomy significantly reduced mean pulmonary artery pressure from 59 mm Hg to 24 mm Hg intraoperatively (p<0.001), with no early postoperative mortality.
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